Deciphering the Mechanisms of Pain in Paget’s (PiP Study)

Kathryn Berg is a Data Manager, at the Institute of Genetics and Molecular Medicine, within the University of Edinburgh. Kathryn attended our information meeting in Nottingham to discuss her work for a pain study, known as Pain in Paget’s (PiP), which has received funding from the Paget’s Association. 
The PiP project aims to achieve greater understanding of the causes of pain in Paget’s disease. The research team will be looking at the bacterial makeup of the mouth and gut, the markers of disease activity in the blood, and the genetics of volunteers recruited from hospitals across the UK.

Kathryn explained that they are looking for 250 volunteers from across the country to help them with this important project. Patients who volunteer to get involved in the study are required to answer a questionnaire, undergo sensory testing, and provide blood and saliva samples. This takes about an hour and a half. Kathryn demonstrated the simple sensory tests and explained why they might help us to understand pain associated with Paget’s disease.
The recruitment of volunteers has already begun in Edinburgh, with 19 volunteers coming into clinic in just three weeks! The study is soon to begin in Glasgow, Liverpool, London and Newcastle. In the near future, there are also plans to recruit from hospitals in Manchester, Middlesbrough, Norwich, Salford, Sheffield and Cardiff.

Whether you have pain or not, you could be an important part of this study. If you are interested in taking part in this research, you can contact the central study team by emailing [email protected] or by phoning 0131 651 8741. They will get in touch with your local research team on your behalf. If you would like to know more, they are happy to send you an information sheet in the post.